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PAGET’S DISEASE – INTRODUCTION

Posted by admin on May 15, 2009

There are some medical conditions which produce typical changes in the body and can be recognised at a glance. One of these is a disorder of bone known as Paget’s disease or osteitis deformans.

Sir James Paget, a London surgeon, first described the condition which bears his name in 1877. Its cause is unknown.

It is rare before the age of 40 but then increases in frequency with age. By the age of 90 at least 10 per cent who have reached this age will have developed this condition in their bones.

Any bone of the body may be affected but it is more common in the skull, in the spine, in the pelvis and the leg bones.

The bones are thickened and yet are softer than normal. And when they bear weight the leg bones may bow outwards. Bone is not a stable tissue.

New bone is continually being laid down and old bone is being continually absorbed or removed by other cells.

*525/71/1*

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